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Xiu Feng Gao

Post time:2017-12-14 Viewed:718


Xiu Feng Gao MD

 微信图片_20171214001537.jpg

Professor, Master and Doctoral Supervisor

Department of Biochemistry and Molecular Biology,

West China School of Basic Medical Sciences & Forensic Medicine, 

Sichuan University. 

Address

No.17 Section 3, People's South Road, Chengdu, 610041

Phone Number

13708087299

E-mail Address

xiufengg@163.com

 

Xiu Feng Gao Graduated from the Bethune medical university in 1983. After graduation she was mainly engaged in clinical work in maternal and child hospital of jilin city since 1983 to 1992. She received medicine doctorate from Tokyo university of Japan in 1999. And then She came to sichuan university as a professor of the 214 talent introduction program at sichuan university in 2004In June 2005, she was awarded the doctoral supervisor of sichuan university.

She was hired as experts of scientific research and reward assessment expert of the national science and technology development center, the ministry of education, the ministry of health and the science and technology department of sichuan province since 2006 to now.

Her main research fields are biosensing technology, protein bioengineering, tumor gene diagnosis and biochemical detection.She has published more than 100 papers including 36 SCI papers so far.

 

Education and Training

1978.08 --- 1983.08   Department of Medicine, Bethune Medical University (Undergraduate)

1983.08 --- 1999.12 Obsterics and Gynecology Hosp[ital Jilin City (Physician)

1993.10 --- 1995.04  Research Center for Advanced Science and Technology, The University of Tokyo, Japan.

1995.04 --- 1999.03   Research Center for Advanced Science and Technology, University of Tokyo, JapanMajor in Biomedical EngineeringMD)

1999.12 --- 2003.01   Medical School, University of North China (Associate Professor)

2003.01 --- Now     Medical School, University of North China (Professor, Master Supervisor)

2004.10-----Now    West China School of Basic Medical Sciences & Forensic Medicine,

Sichuan University (Professor, Master and Doctoral Supervisor)

2007---------Now    National Science and Technology Awards Evaluation Expert

Science and Technology Evaluation Expert (Health Ministry)

Science and Technology Evaluation Expert ( Sichuan Province)

 

Area of Interest

Biosensor Technology, Protein Bioengineering, Research and Development of Biochemistry Assay Method.

Admissions Directory

Postgraduate071010 Biochemistry And Molecular Biolog

1001Z1 Medical Biochemistry And Molecular Biolog

Doctoral Student071010 Biochemistry And Molecular Biolog

1001Z1 Medical Biochemistry And Molecular Biolog

 

Publicatied Papers

  1. Yong Sheng Li, and Xiu Feng Gao, Flow injection      analysis and its applications of clinic analyses, Academic Journal of Medical Testings of Shanghai, 1989, 4(4):      231.

  2. Yong Sheng Li and Xiu Feng Gao, Application of FIA      for clinic assays, Foreign Medicine: Fascicle      of Clinical Biochemistry, 1989, 10(5): 21.  

  3. Yong Sheng Li and Xiu Feng Gao, Relationships of      exponents with coefficients of equations on axial and radial dispersions      in flow injection analysis, Laboratory Robotics and Automation (Wiley & Sons), 1996, 8(3):      171-179.

SCI: VC432 (IF: 0.614)SCI-1;EI: 96093331036EI-1

  1. Yong Sheng Li and Xiu Feng Gao, Two new      parameters---Axial degree and radial dispersions intensity of the sample      zone injected in flow injection analysis, Laboratory Robotics and      Automation (Wiley & Sons), 1996, 8(6): 351-360.

SCI: WD692 (IF: 0.614) SCI-2EI: 97023536919EI-2

  1. Xiu Feng Gao, K. Ikebukuro, I. Karube, Yong Sheng Li, A novel assay for      determination of sulfated bile acids in urine by use of flow-injection      chemiluminescence principle with immobilized enzymes, Laboratory      Robotics and Automation (Wiley & Sons), 1997, 9(2): 69-79.  

SCI: WZ161    (IF: 0.614) S CI-3     EI: 97063686195. EI -3

  1. Xiu Feng Gao, K. Ikebukuro, I. Karube, Yong Sheng Li, Determination for      sulfated bile acids using immobilized enzyme reactor based on FIA      chemiluminescence, Bunseki kagaku, 1997, 46(5): 357-365.

SCI: XA960 (IF: 0.441) SCI-4EI: 97073753215EI-4

  1. Xiu Feng Gao, Development of a determination method for sulfated bile acids in      urineBunseki kagaku, 2000, 49(11): 807.

SCI: 2001, XB 960 (IF: 0.441) SCI-5

  1. Xiu Feng Gao, Yong Sheng Li, Isao Karube, Flow injection spectrophotometric      determination of sulfated bile acids in urine with immobilized enzyme      reactors using the water soluble tetrazolium blue-5, Anal. Chim. Acta, 2001, 443, 257-264.

SCI: QT487 (IF: 2.730) SCI-6

  1. Xiu Feng Gao,      Yong Sheng Li, Isao Karube, A flow injection chemiluminescence method for      determination of sulfated bile acids in urine by using an on-line      immobilized enzyme reactor, Chinese      J. Analytical Chemistry, 2001, 29(10):1154-1156.

SCI: DY472 (IF: 0.288) SCI-7

  1. Xiu Feng Gao, Yong Sheng Li, Isao Karube, Development of rapid analytical      method for the determination of sulfated bile acids in urine based on      flow-injection spectrophotometry by using immobilized enzyme technology      (in Japanese), Bunseki Kagaku,      2003, 52(3):195-200.

SCI: QF655 (IF: 0.441) SCI-8

  1. Xiu Feng Gao and Yong Sheng Li, Statistical analysis and determination of zinc      and iron ion in hair of pregnancy women and neonates., Chinese Journal of General Medicine,      2003, 5(5): 16-17.

  2. Xiu Feng Gao and Yong Sheng Li, Rapid determination of chloride ion in serum      based on flow-injection spectrophotometry, Chinese Journal of Today’s Medicine, 2003, 3(12): 20-22.

  3. Yong      Sheng Li, Xiu Feng Gao, Jiao-Na      Qi, Zheng Xiao, Research on the alcohol      fluorescence capillary biosensor, Liquor-making Science Technology, 2006, 145(7): 34-36.

  4. Yong      Sheng Li, Jiao Na Qi, Xiu Feng Gao,      Research advance of methanol determination methods for wines, Liquor-making Science Technology,      2006, 139(1): 84-89.

  5. Xiu Feng Gao, Yong      Sheng Li*, Yan-Xia Jiang, Research on fluorescence capillary analysis of      DNA marked by using Cy-5 reagent, Chinese J. Anal. Chem,      2006, 34(9): S220-222.

SCI: XH140 (IF: 0.361) SCI-9

  1. Yong Sheng Li, Xiu Feng Gao, Research on the immobilized enzyme alcohol      fluorescence capillary analysis,      J. Sichuan University (Engineering      science edition) , 2007, 39(1): 74-77. EI: 071510546786EI-5

  2. Yong Sheng Li and Xiu Feng Gao*, Determination of      various alcohols based on a new immobilized enzyme fluorescence capillary      analysis. Anal. Chim. Acta,      2007, 588 (1):140-146.

SCI: IR154 (IF: 3.186)SCI-10

  1. Yong      Sheng Li, Xiu Feng Gao, A      new method for chemical analysis: fluorescence capillary analysis, Spectroscopy and Spectral Anal., 2007, 27(8): 1565-1569.

SCI: LG207 (IF: 0.843) SCI-11 EI: 073810820015 EI-7

  1. Yong Sheng Li, Xiang Ju, Xiu Feng Gao*,Yuan-Yuan Zhao,      Yan-Fei Wu, Immobilization      enzyme fluorescence capillary analysis for determination of lactic acid, Anal. Chim. Acta, 2008, 610, 249-256.

SCI: WB275   (IF: 3.186)SCI-12; EI: 080811109320EI-8

  1. Yuan-Yuan Zhao, Xiu Feng      Gao, Yong Sheng Li, Xiang Jua, Jia Zhang, Jia Zheng, Determination of      pyruvic acid by using enzymic fluorescence capillary analysis, Talanta, 2008, 762): 265-270.     

SCI: CX321 (IF: 3.374)SCI-13EI: 082211283516EI-9

  1. Yong Sheng Li, Wei Ping Liu, Xiu Feng Gao*, Dan Dan Chen, Wei Guang Li, Immobilized      enzymatic fluorescence capillary biosensor for determination of sulfated      bile acid in urine, Biosensors &      Bioelectronics, 2008,      24,      538-544.      

SCI:PB377 (IF:5.143) SCI-14EI:  20084111631372EI-10

  1. Yun      Dong Du Xiu Feng Gao and Yong Sheng Li*, Determination of      glucose by enzyme fluorescence capillary analytical method, Chinese J. Anal. Chem., 2008, 36(7):991-994 .

SCI: PL344 (IF: 0.633) SCI-15

  1. Wei Ping Liu, Xiu Feng Gao and Yong Sheng Li*, Micro-quantitative fluorimetric analysis for determination of sulfated      bile acid in urine, Chinese J. Anal. Lab., 2008, 27(5): 13-16.

  2. Yong      Sheng Li*, Xiu Feng Gao, Research on a flow injection      analysis system for the simultaneous determination of silicate and phosphate, J. Sichuan University (Engineering science edition), 2008, 40(4): 62-65.

EI: 071510546786EI-11

  1. Quan Yu Yang, Yong      Sheng Li, Xiu Feng Gao*, Yan-Jun Wang, Ke Jin , Rui Zhao, Preparation and Appl ication of DNA      Fluorescence Capillary Biosensor Labelled with Berberine, PTCA ( Part b      :chem. Anal. ), 2008, 44(6): 491-494.

  2. Quan Yu Yang, Yong      Sheng Li, Xiu Feng Gao*, Yan Jun Wang, Ke Jin , Rui Zhao, Staining effect      of fluorochrome berberine hydrochloride on nucleic acid in Gels. Journal of      Instrumental Analysis, 2008, 27(9): 968-972.

  3. Yan Jun Wang, Yong Sheng Li, Quan Yu Yang, Yi      Huang, Jing Tang, Xiu Feng Gao *, Research on DNA fluorescence capillary biosensor marked by Goldview. Spectroscopy and      Spectral Analysis, 2009, 29(1): 165-168.

SCI: 395JU (IF: 0.843) SCI-16EI: 20090711909839EI-12

  1. Ping Hang, Xiu Feng Gao*, Hong      Xia Gao, Su ping Zheng, Knocking-down Nucleostemin Gene Expression by RNA      interference Technique      on the A549 Cells, Medical Journal of West China, 2009, 21(7): 1082-1084.

  2. Bai Lin Zhou, Xiu Feng      Gao*, Xiao Ting Wu, Xu Guang Zhao, Yong Sheng      Li, Jian      Wang, Extraction of and Research on Cytosolic      Aldehyde Dehydrogenase from Saccharomyces cerevisiae, Liquor-making      Science Technology, 2009, 180(6): 28-30.

  3. Xiao Ting Wu, Xiu Feng      Gao*, Bai Lin Zhou, Xu Guang Zhao, Yong Sheng      Li, Ying Gong, Comparing      Aqueous two-phase Extraction with DEAE-32 Chromatography on Purified      Process of Alcohol Dehydrogenase from Saccharomyces cerevisiae, Liquor-making      Science Technology, 2009, 139(1): 84-89.

  4. Yong Sheng      Li, Xiang Ju, Xiu-Feng Gao*,      Wei Yang, A novel immobilization enzyme lactate fluorescence      capillary biosensor, Chin. J. Anal.      Chem., 2009, 37(5): 637-642.

SCI: 450FD    (IF: 0.790) SCI-17

  1. Xiang Ju, Xiu Feng Gao, Yong Sheng Li*, Wei      Yang, Research on determination of lactic acid based on liquid-enzyme      fluorescence capillary analysis, Chin.      J. Anal. Lab., 2009, 28(1): 120-122.

  2. Ran Fei      Wei, Yong Sheng Li*, Xiu Feng Gao, Heng Wang, Yuan Fang, Research on the      determination of horseradish peroxidase      activity by circulating      continuous flow analysis, Chin.      J. Anal. Chem., 2009, 37(6), 897901.

SCI: 462VL (IF: 0.790) SCI-18

  1. Yong Sheng Li, Yun Dong Du,      Ting Mei Chen and Xiu Feng Gao*,      A novel glucose fluorescence capillary biosensor based on multienzyme      immobilization and fluorescence capillary analysis, Biosensors & Bioelectronics, 2010, 25(6): 13821388.

SCI: 559YO (IF: 5.443) SCI-19

  1. Heng Wang, Yong Sheng Li*, Xiu Feng Gao, Tian TianA recirculating-catalysis      flow analysis method for determination of activity of alcohol dehyrogenase,      Liquor-Making Science &      Technology,      2010, 196(10), 100-114.

  2. Heng Wang, Yong Sheng Li*, Xiu Feng Gao, Determination of activation      energy for guajacolum- horseradish peroxidase-H2O2 system by recirculating-catalysis      flow Analysis, Chinese Journal of      Spectroscopy Laboratory, 2011, 28(2), 489-493.

  3. Yong Sheng Li, Wei Yang,      Qiao Jing Li, Lang Zhou, Xiu Feng      Gao*, Enzyme fluorescence capillary analysis for simultaneously      determining trace-level pyruvateand lactate based on forward and reverse      reactions of pyruvate/NADH/LDH/NAD+/lactate system, Chin. J. Anal. Chem., 2011, 39 (7): 1058-1064.

SCI: 805WU (IF: 0.941) SCI-20

  1. Qiao Jing Li, Xiu Feng Gao*, Yun Dong Du, Ting      Mei Cheng, and Yong sheng Li *, Determination of blood glucose by fluorescence      capillary analysis based on glucose/ glucose oxidase/H2O2/L-tyrosine/      horse radish peroxidase reaction system, Chin. J. Anal. Chem., 2011, 39(8): 1181-1185.

SCI: 842LB (IF: 0.941) SCI-21

  1. Lei Zhou, Zhen-Yao Lai, Hui      Sheng Zhang, Xiu Feng Gao and      Yong Sheng Li *, An automatic flow-injection micro-electrode      electrochemical analysis system for simultaneous determination of four      kinds of serum electrolytes, Chin. J.      Anal. Chem., 2011, 39(6): 809-814.      

SCI: 810BC (IF: 0.941) SCI-22

  1. Ting      Mei Chen, Yong Sheng Li* and Xiu Feng      Gao, Determination of blood glucose based on a fluorescence reaction      system of glucose oxidase-horseradish peroxidase- glucose-guaiacol, Chinese J. Analysis Laboratory, 2011, 30(8): 6-10.

  2. Wei ping Liu, Xiu Feng Gao*, Research      developments on determination methods of sulfated bile acids in urine , Laboratory Medicine, 2011, 26 (2):      139-141.

  3. Yan jun Wang, Yong Sheng Li, Xiu Feng      Gao*, Quan yu Yang, Study on DNA Fluorescence Capillary B      iosensor Labeled w ith Cy5, Labeled      Immunoassays & Clin.Med, , 2011, 18(3): 182-185.

  4. Qiao-Jing      Li, Yong-Sheng Li, Lang Zhou, Wei Yang, and Xiu-Feng Gao*, A Novel Enzyme Fluorescence Capillary Analysis      for the Determination of Lactate Dehydrogenase Activity in Micro-Volume      Serums, Chin. J. Anal. Chem., 2012, 40(6),      1043-1047.

SCI: 074NE (IF: 0.941) SCI-23

  1. Lang      Zhou, Qiao Jing Li, Yong Sheng Li* and Xiu Feng Gao, Lysing-heating fluorescence capillary analysis      used for the rapid determination of pyruvate in erythrocytes, Chin. J. Anal. Chem., 2012, 2012, 40(11),      1725-1729.

SCI: 074SE (IF: 0.941) SCI-24

  1. Yong Sheng Li, Hui-Sheng Zhang, Lei Zhou, Zhen Yao      Lai, Xiu Feng Gao*, A      negative-pressure double-lines flow-injection ion-selective electrode      method for simultaneous determination of K+, Na+,      Cl-, Ca2+ in serums, J. Sichuan University (Engineering science edition), 2012, 44(4):169-175.

EI: 20123515381975 EI-13

  1. Yong Sheng      Li, Lei Zhou, Hui Sheng Zhang, Zhen Yao Lai and Xiu Feng Gao*, A Negative-pressure Flow-injection      Micro-electrode System for Rapid and Simultaneous Determination of Four Electrolytes      in Human Serums, Anal. Science,      2012, 28(8), 781-787.

SCI 998ZA (IF: 1.569) SCI-25

  1. Hong Xia      Gao, Xiu Feng Gao*, Guo Qing Wang      , En Shu Wang, Wei Huang, and Ping Huang, In vitro study of nucleostemin gene      as a potential therapeutic target for human lung carcinoma, Biomed Environ Sci., 2012, 25(1): 91-97.

SCI (IF: 1.154) SCI-26

  1. Wei      Hang, Xiu Feng Gao*, Gao Hong      Xia,, Ping Hang, Effect of Knocking-down Nucleostemin Gene Expression by      RNA interference      Technology for the U251 Cells, Modern      Preventive Medicine, 2012, 39(6): 1477-1480.

  2. Hai      Sheng Bao, Xiu Feng Gao, Xue Ni      Zheng, Yong-Sheng Li,      Preparation and properties of chitosan immobilized zinc ionaffinity      chromatography matrix, China      Biotechnology, 201232( 5): 85-90.

  3. Hai      Sheng Bao, Xiu Feng Gao, Xue Ni      Zheng, Yong-Sheng Li,      Purification of aldehyde dehydrogenase with histidine-tagged by      immobilized metal ion affinity chromatography with chitoan used as      substrate, Liquor-Making Science      & Technology, 20122(212): 27-29.

  4. Xue      Ni Zheng, Xiu Feng Gao, Yong Sheng      Li, Cloning of Aldehyde Dehydrogenase Gene aldC and Expression of Bacillus      halodurans XJU -1, Liquor-Making      Science & Technology, 20123(213): 43-45.

  5. Zhao      Zhang, Yong Sheng Li*, Xiu Feng      Gao, Study on purification and properties of peroxidase from shatian      pomelo (in Chinese), Science and      Technolog y of Food Industry, 2013, 34(12): 187-191.

  6. Lin Hong, Xiu      Feng Gao*, Jian-min Chen, Lin Hu, Yong Sheng      Li, Cloningexpression      and biological activity      of the bile acid sulfate sulfatase gene BSS H1, Basic      Clinical Medicine, 2013, 33 (7): 876-880.

  7. Yang      Zhao, Yong-Sheng Li*, Xiu Feng Gao,      A new method for accurately determining peroxidase activity based on      fluorescence decrease of guaiacol, Chinese      J. Anal. Chem., 2015, 43(7), 1040-1046.

SCI: CT4UY (IF: 0.941) SCI-27

  1. Guo      Qing Wang, Xiufeng Gao*, Hong Xia Gao, Hai Sheng Bao, Yan Liu and      Yong Sheng Li*, Heterologous expression and purification of aldehyde      dehydrogenase gene from Bacillus halodurans XJU-1, Technology and Health Care, 201523S49–S53.

SCI: CJ1AU (IF: 0.697)SCI-28

  1. Jian Min      Chen , Xiu Feng Gao*, Lin Hong,      Li Ting Ma, Yong Sheng Li*, Expression,      purification and functional characterization of a novel 3a-hydroxysteroid      dehydrogenase from Pseudomonas aeruginosa, Protein Expression and Purification, 2015115, 102–108.

SCI: CT2HS (IF: 1.695)SCI-29

  1. Qiao Jing      Li, Yong Sheng Li, Xiu      Feng Gao*, A Novel Analysis Method for Lactate Dehydrogenase Activity      in Serum Samples Based on Fluorescence Capillary Analysis, Analytical Sciences, 2015,      5(31):413-419.

SCI:)074NE (IF:1.25) SCI-S30

  1. Yue-Jiao      Wang, Bin Wang, Xiu Feng Gao,      Yong Sheng Li*, Research on bovine serum albumin composite membrane based      on electrostatic interactions with layer-by-layer self-assembly (in      Chinese), PTCA (Part B: Chem. Anal.),      2015, 51(5):630-633.

  2. Li      Ting MaXiu Feng Gao*, Yin Ji WangJia Xin Pan, Jia Hao Zhao, Wen Long Yang, Vector      constructionexpression      and purification of Erythropoietin, Medical Journal of  West China, 2015, 8(27): 1131-1134.

  3. Yong      Sheng Li, Wei Zheng, Xiu Feng Gao*,      A new method for rapid and automatic determination of peroxidase activity      based on the ratio of flow-injection residence time and absorbance (in      Chinese), Chinese J. Anal. Chem., 2015, 43 (10): 1580-1588.

  4. Yang Zhao, Yong Sheng Li*, Xiu Feng Gao, A new method for      accurately determining peroxidase activity based on fluorescence decrease      of guaiacol, Chinese J. Anal. Chem.,      2015, 43(7): 1040-1046.

SCI: CT4UY (IF: 0.941) SCI-31

  1. Bin Wang, Yue Jiao Wang, Xiu Feng Gao, Yong Sheng Li*.      Utilization of parameters developed in layer-by-layer fabrication of      proteincontaining films for enzyme immobilization, Journal of Biomaterials Science, Polymer Edition, 2015,      26(17): 1312-1326.  SCI: CT3SA (IF: 1.648)SCI-32

  2. Yong Sheng      Li, Wei Zheng, Xiu Feng Gao, A new method for rapid and      automatic determination of peroxidase activity based on the ratio of      flow-injection residence time and absorbance, Chinese J. Anal. Chem., 2015, 43(10): 1580-1588.

SCI: (IF: 0.941) SCI-33

  1. Jia Xin Pan, Xiu Feng Gao*, Jia Hao Zhao, Ya Xiong      Luo, Xiao Ting Wu, Yong Sheng Li,The Vector construction, separation, purification      and activity detection of human-derived erythropoietin, Chongqing Medicine, 2016, 28(10):      3913-3915.

  2. Jing ZhaoYong Sheng Li*Xiu Feng Gao, A rapid method for the determination of melamine in dairy      products based on gold nanoparticles and flow injection analysis      spectrophotometry, Chinese Journal      of Analysis Laboratory, 2016, 35(8): 961965.

  3. Lin Can Shi, Yong Sheng Li*, Xiu      Feng Gao, Online monitoring of organic pollutants and inorganic ion      contents in the process of reverse osmosis membrane cleaning, Chinese Journal of Analysis Laboratory,      2016, 35(7): 841845.

  4. Yong Sheng Li*, Lin Can Shi, Xiu Feng Gao, Jian Gang Huang,      Cleaning effects of oxalic acid under ultrasound to the used reverse      osmosis membranes with an online cleaning and monitoring system, Desalination, 2016, 390: 62-71.

SCI: DM9OS (IF: 4.412) SCI-34

  1. Wei Zheng, Yong Sheng Li*, Yang Zhao, Xiu Feng      Gao, The activity assay of peroxidase in radishes on FIA-Spectrophotometry, Physical Testing and Chemical      Analysis Part B:Chemical Analgsis, 2016, 52(10):1155-1159.

  2. Yong-Sheng      Li*, Qiao Jing Li, Wei Yang, Xiu Feng      Gao. Research on a new micro-volume fluorescence capillary biosensor      assay for sequentially quantifying pyruvate and lactate, J. Fluoresc, 2017, 27: 883-894. SCI: ES3BZ (IF: 1.4609)SCI-35

  3. Jia      Hao Zhao, Xiu Feng Gao*, Ya Xiong      Luo, Xiao-ting Wu, Yong Sheng Li, Site-directed mutagenesis and activity      investigate of Erythropoieti, Genomics      and Applied Biology, 2017, 36(12)

  4. Ya      Xiong Luo, Qiao Jing Li, Lang Zhou, Yong Sheng Li and Xiu Feng Gao*, Florescence capillary biosensor based on      self-assembled AuNPs/LDH for micro-volume intracellular pyruvate,analyst,      2017,12, Accepted. SCI收录 (IF: 3.885) SCI-36

 

Patents

1.       Yong-Sheng Li and Xiu-Feng Gao, Fluorescence capillary reaction device and fluorescence capillary analysis, 2005, No.200510021542.8Authorization day: 2011-11-23.

2.       Yong-Sheng Li and Xiu-Feng Gao, The fluorescence capillary analysis method and the enzyme fluorescence quantitative reagent kit for the sulfated bile acid, 2008, No.200810045260.5; Authorization day: 2010-12-01.